Scientists hail autoimmune disease therapy breakthrough :
Authors of new study speculate that therapy at its heart led to a ‘rebooting of the immune system’
irishtimes.com/health/2022/09/15/scientists-hail-autoimmune-disease-therapy-breakthrough/
Photo: irishtimes.com · view article
Breakthrough Therapy Remits Severe Autoimmune DiseaseFive lupus patients treated with gene-modified cells have remained symptom-free for 3 to 17 months post-therapy.
Key FactsSep 16, 2022 · Reading time: ~30 sec.
Summary created with AI assistance · Source: irishtimes.com
Summary created with AI assistance · Source: irishtimes.com
- Five individuals with severe lupus underwent CAR T-cell therapy that induced disease remission.
- The treatment targeted and eliminated malfunctioning B cells responsible for producing harmful autoantibodies.
- Symptoms such as arthritis, fatigue, and organ inflammation resolved significantly after the procedure.
- Patient immune responses to vaccines remained intact, suggesting the therapy selectively targets disease-causing cells.
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inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.
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