Berlin's Charité: First patient in Germany treated with gene-editing technology
spiegel.de/wissenschaft/medizin/berliner-charite-erstmals-patient-in-deutschland-mit-genschere-behandelt-a-cdd17372-61a2-423e-8ce9-eba8c072fbc1
Photo: spiegel.de · view article
Charité Reports Germany’s First Regular Crispr TreatmentCharité says 19-year-old Mohammed, who has beta-thalassemia, no longer depends on blood transfusions.
Key FactsOct 1, 2026 · Reading time: ~45 sec.
Summary created with AI assistance · Source: spiegel.de
Summary created with AI assistance · Source: spiegel.de
- Charité says Mohammed was Germany’s first patient to receive a Crispr-based medicine in regular treatment.
- Casgevy was first administered to him in May 2026, and the treatment is expected to last about twelve months.
- The procedure involved infusing 900 million genetically modified stem cells; full hemoglobin production is expected after about six months.
- The treatment requires 15 years of follow-up because Charité says long-term safety and efficacy data remain unavailable.
We also still have no data on the long-term safety and efficacy of the gene therapy.— Lena Oevermann, Charité physician and head of the program for hemoglobinopathies
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Berlin's Charité: First patient in Germany treated with gene-editing technology
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