Ovarian Cancer Risk Doubled by Estrogen-Only HRT:
New research found that estrogen alone increases ovarian cancer risk in postmenopausal women with prior ...
medscape.com/s/viewarticle/ovarian-cancer-risk-doubled-estrogen-only-hrt-2024a1000b2p
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Key FactsOvarian Tumor Risk Doubled by Estrogen-Only HRT
Jun 13, 2024 · Reading time: ~30 sec.
Summary created with AI assistance · Source: medscape.com
Summary created with AI assistance · Source: medscape.com
- Two decades after the groundbreaking Women's Health Initiative (WHI), new findings show that estrogen-only therapy doubles the risk of ovarian cancer in postmenopausal women.
- An analysis of two WHI studies revealed that estrogen-only therapy significantly increased the risk of ovarian cancer, while the combination of estrogen and progesterone did not pose an increased risk and even reduced the risk of endometrial cancer.
- The new findings should lead to changes in practice and guidelines regarding the use of estrogen alone in ovarian cancer survivors.
- The WHI studies have shown that combined therapy, not estrogen alone, is associated with an increased risk of breast cancer, reassuring the use of estrogen alone. The study is considered a valuable resource that continues to provide insights to help women even after decades.
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