mayocl.in Apr 02 24
New study finds triple-negative breast cancer tumors with an increase in immune cells have lower risk of recurrence after surgery
newsnetwork.mayoclinic.org/discussion/new-study-finds-triple-negative-breast-cancer-tumors-with-an-increase-in-immune-cells-have-lower-risk-of-recurrence-after-surgery/
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Immune Cells Reduce Recurrence Risk in Breast CancerAnalysis of 1,966 early-stage TNBC patients reveals higher immune cell counts link to 95% survival five years post-surgery.
Key FactsApr 2, 2024 · Reading time: ~45 sec.
Summary created with AI assistance · Source: newsnetwork.mayoclinic.org
Summary created with AI assistance · Source: newsnetwork.mayoclinic.org
- Early-stage triple-negative breast cancer patients with elevated tumor-infiltrating lymphocytes (TILs) show lower recurrence rates without chemotherapy.
- Nearly 2,000 participants were followed for a median of 18 years in this international study.
- TIL presence may become a standard prognostic biomarker to guide treatment decisions in TNBC.
- Detecting immune cells visually under a microscope adds no extra cost, aiding use in low-resource settings.
This is an important finding because it highlights that the abundance of TILs in breast tissue is a prognostic biomarker in people with early-stage triple-negative breast cancer, even when chemotherapy is not administered.— Roberto Leon-Ferre, M.D., a breast medical oncologist at Mayo Clinic Comprehensive Cancer Center and first author of the study.
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Study finds triple-negative breast cancer tumors with increased immune cells have lower risk of recurrence after surgery
medicalxpress.com/news/2024-04-triple-negative-breast-cancer-tumors.html
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