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Single-Dose Zilebesiran Cuts BP Out to 6 Months: KARDIA-2: This phase 2 study supports the potential for combining biannual dosing of zilebesiran with ...
medscape.com/viewarticle/single-dose-zilebesiran-cuts-bp-out-6-months-kardia-2-2024a100073r
Single-Dose Zilebesiran Cuts BP Out to 6 Months: KARDIA-2
Quick Glance: Zilebesiran: Long-Term Blood Pressure Reduction in KARDIA-2
  • Administering a single subcutaneous dose of the RNA interference agent zilebesiran resulted in significant decreases in systolic blood pressure compared to placebo at 3 months when incorporated into a standard antihypertensive therapy in the KARDIA-2 study.

  • These effects persisted for up to 6 months in the majority of patients, despite the addition of supplementary antihypertensive treatment.

  • Regarding side effects, treatment with zilebesiran was linked to higher rates of mild hyperkalemia, hypotension, and a decrease in estimated glomerular filtration rate, with most cases being non-severe, temporary, and resolving without intervention.

  • The detailed outcomes of the KARDIA-2 study were unveiled by Akshay Desai, MD, a cardiologist at Brigham and Women's Hospital in Boston, Massachusetts, during the recent American College of Cardiology Annual Scientific Session held in Atlanta, Georgia.
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What are the financial pros and cons of retiring in Minnesota?: The state has higher taxes. But it is also important to look at the "whole picture."
startribune.com/retirement-minnesota-financial-planning-taxes-social-security/600358313/
What are the financial pros and cons of retiring in Minnesota?
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Swapping Salt with Substitutes May Lower Your Risk of Death from Heart Disease: Replacing regular salt with healthier substitutions may help lower your risk of ...
healthline.com/health-news/salt-substitutes-heart-disease-risk
Swapping Salt with Substitutes May Lower Your Risk of Death from Heart ...
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Aussies smash Americans for pro-gun agenda: The prospect of armed guards at shopping centres could carry a “risk” to the public, NSW’s top cop says ...
news.com.au/national/nsw-act/crime/aussies-defend-gun-laws-after-bondi-junction-massacre/news-story/308138b18fb64ffc3a9b9d5949e69035
Aussies smash Americans for pro-gun agenda
Profile picture of Healthline
Not Getting Enough Sleep May Raise Hypertension Risk, Especially for Females: New research suggests that sleeping less than seven hours a night may increase the ...
healthline.com/health-news/not-getting-enough-sleep-hypertension-risk
Not Getting Enough Sleep May Raise Hypertension Risk, Especially for ...
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Biden administration approves new background check rules for firearms sales: It's the largest expansion of background checks for gun purchases in decades.
trib.al/s690aCJ
Biden administration approves new background check rules for firearms ...
Quick Glance: Biden Administration Implements Stricter Background Checks for Gun Dealers
  • A new rule by the Biden administration will require thousands of gun dealers to conduct background checks on buyers to close a legal loophole.

  • President Biden emphasizes that the measure aims to keep guns away from domestic abusers and felons to save lives.

  • The law mandates that sellers primarily engaged in selling firearms for profit must be federally licensed and perform checks.

  • Despite praise from advocates, the regulation is likely to face legal challenges from gun rights activists, concerned about potential infringements.
Profile picture of TRT World
Sydney mall attacker had mental illness, 'nothing' to suggest terror motive
trtworld.com/australia/sydney-mall-attacker-had-mental-illness-nothing-to-suggest-terror-motive-17771144
Sydney mall attacker had mental illness, 'nothing' to suggest ...
Quick Glance: Bondi Junction Shopping Centre Stabbing Victims
  • Faraz Tahir, 30, fatally stabbed while working as a security guard by Joel Cauchi, 40.

  • Five women and one man were killed, including Tahir, 30.

  • Victims identified include Faraz Tahir, Ashlee Good, Dawn Singleton, and Jade Young.

  • Three individuals remain critical, eight are stable, and one victim has been discharged.
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Man, 52, who started drinking at nine celebrates being one year sober: Darren Bell, 52, spent 43 years of his life in active addiction and nearly died as a ...
grimsbytelegraph.co.uk/news/grimsby-news/grimsby-man-52-who-became-9208135
Man, 52, who started drinking at nine celebrates being one year sober
Profile picture of The Atlanta Journal-Constitution
It's almost April 15. Here's how to reduce stress and get your taxes done: NEW YORK (AP) — For many people, tax season isn't only about gathering W-2 forms ...
ajc.com/news/nation-world/its-almost-april-15-heres-how-to-reduce-stress-and-get-your-taxes-done/63IMCVDOOBBO3HZVNHNLZQJMPI/
It's almost April 15. Here's how to reduce stress and get your taxes done
Profile picture of Neue Zürcher Zeitung
Generation Z: Jonathan Haidt fears that they will cause democracies to falter: Haidt has written a book about Generation Z. He fears that their high internet ...
nzz.ch/feuilleton/interview-jonathan-haidt-covid-war-nichts-im-vergleich-zu-dem-was-wir-unseren-kindern-mit-sozialen-medien-und-smartphones-antun-ld.1824924
Generation Z: Jonathan Haidt fears that they will cause democracies to ...
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Jelly Roll shares how he lost 70 pounds, and how much more weight he hopes to lose
goodmorningamerica.com/wellness/story/jelly-roll-shares-lost-70-pounds-weight-hopes-109242501
Jelly Roll shares how he lost 70 pounds, and how much more weight he hopes ...
Profile picture of ITVX
'We'll make it I swear': Bon Jovi on major throat surgery and putting their mental health first
itv.com/news/2024-04-16/bon-jovi-on-major-throat-surgery-and-putting-their-mental-health-first
'We'll make it I swear': Bon Jovi on major throat surgery and putting ...
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89 percent of all heart patients make a serious mistake: Too much salt is bad for your health - especially when it comes to cardiovascular diseases ...
focus.de/gesundheit/ratgeber/herz/risiko/bluthochdruck/neue-studienergebnisse-sie-essen-zu-viel-salz-das-kann-der-grund-fuer-herz-kreislauf-erkrankung-sein_id_259833277.html
89 percent of all heart patients make a serious mistake
Profile picture of DW-TV
Sydney stabbing: Police say no ideological motivation : Australian authorities, who have identified the attacker in the Sydney stabbing spree ...
dw.com/en/sydney-stabbing-police-say-no-ideological-motivation/a-68813540
Sydney stabbing: Police say no ideological motivation
Profile picture of Daily Mirror
Physically healthy 28-year-old woman schedules euthanasia due to depression: A 28-year-old woman from the Netherlands who suffers with severe mental health ...
themirror.com/news/world-news/physically-healthy-28-year-old-419986
Physically healthy 28-year-old woman schedules euthanasia due to ...
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How exercise strengthens your brain: People who work out regularly report having better mental health than people who are sedentary.
straitstimes.com/life/how-exercise-strengthens-your-brain
How exercise strengthens your brain
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The key to a long life? ‘Undereating’ and ice baths, says 88-year-old Gary Player, still spritely at 88th Masters
cnn.com/2024/04/11/sport/gary-player-the-masters-long-life-spt-intl/
The key to a long life? ‘Undereating’ and ice baths, says 88-year-old Gary ...
Quick Glance: Tiger Woods Sets Record
  • At this year's Masters in Augusta, Georgia, attention was on whether Tiger Woods would make the cut.

  • Woods finished his opening rounds with a 1-over-par and an even-par, securing him comfortably above the cut line.

  • His score was well above the projected cut, marking his 24th consecutive cut, a tournament record.

  • As one of 27 players still on the course, Woods had a grueling day, mentioning fatigue after playing 23 holes.
Profile picture of ITVX
Adam Peaty on how his faith got him through mental health struggle and back in the pool
itv.com/news/2024-04-16/adam-peaty-faith-got-me-out-of-depression-struggle-and-back-in-the-pool
Adam Peaty on how his faith got him through mental health struggle and ...
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Your Guide to Blurry or Hazy Vision: Blurry vision is a disturbance in your eyesight that makes it difficult to see. Learn more about the causes, symptoms ...
healthline.com/health/hazy-vision
Your Guide to Blurry or Hazy Vision
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Medical Conditions and Lifestyle Factors that Can Damage Your Kidneys: Some medical conditions, medications, and lifestyle habits can cause damage to your ...
healthline.com/health/what-can-cause-damage-to-your-kidneys
Medical Conditions and Lifestyle Factors that Can Damage Your Kidneys
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Consequences of aging, why we die explained by Nobel biologist: Ramakrishnan explains why we may not want to lengthen our lives much longer.
abcnews.go.com/US/consequences-aging-die-explained-nobel-biologist/story
Consequences of aging, why we die explained by Nobel biologist
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What Are Vivid Dreams and Why Do I Have Them?: Sometimes we wake up and have no idea that we’ve dreamed. Vivid dreams are those we can closely recall because ...
healthline.com/health/vivid-dreams-causes
What Are Vivid Dreams and Why Do I Have Them?
Profile picture of TRT World
Broken minds, broken hearts: Gaza’s mental health emergency: Israel’s brutal and long-drawn war in the Palestinian enclave has devastated the lives of civilians ...
trtworld.com/opinion/broken-minds-broken-hearts-gazas-mental-health-emergency-17784732
Broken minds, broken hearts: Gaza’s mental health emergency
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Why Chick-fil-A Is Allowing Antibiotics in Chicken and How It May Affect You: Chick-fil-A announced it will now allow some antibiotics in its chicken ...
healthline.com/health-news/why-chick-fil-a-is-allowing-antibiotics-in-chicken-and-how-it-may-affect-you
Why Chick-fil-A Is Allowing Antibiotics in Chicken and How It May Affect ...
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Wild reason Aussie won’t work full time: Jordan Stacey is only 24 and has already decided she doesn’t want to work full-time ever again.
news.com.au/finance/work/careers/young-aussie-reveals-her-plan-to-never-work-a-fulltime-job-again/news-story/e3c99989d695e283874ccd96b47431de
Wild reason Aussie won’t work full time
Profile picture of Daily Mirror
Vinnie Jones opens up on 'fantastic' new love after heartbreak of losing wife : Vinnie Jones lost his beloved wife Tanya to skin cancer in 2019 ...
mirror.co.uk/3am/celebrity-news/vinnie-jones-opens-up-fantastic-32505467
Vinnie Jones opens up on 'fantastic' new love after heartbreak of losing ...
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Tragedy as dad 'with so much love to give' is found dead after going missing: Joe Phipps, of Honeybourne, Worcestershire, believed "if he passed away no one ...
mirror.co.uk/news/uk-news/tragedy-dad-23-with-much-32535513
Tragedy as dad 'with so much love to give' is found dead after going ...
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In 2021, Ethan Crumbley went to school with a gun. Now, his parents are going to jail
abc.net.au/news/2024-04-10/ethan-crumbley-parents-jailed-for-school-shooting/103689552
In 2021, Ethan Crumbley went to school with a gun. Now, his parents are ...
Profile picture of ITVX
'It's distressing': Mental health patients twice as likely to wait 12 hours in A&E
itv.com/news/2024-04-11/mental-health-patients-twice-as-likely-to-wait-12-hours-in-a-and-e
'It's distressing': Mental health patients twice as likely to wait 12 ...
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Kate Middleton suffers professional setback: opinion: In 1981, then-Prince Charles’s private secretary Michael Colborne tried to prepare sacrificial lamb and the ...
news.com.au/entertainment/celebrity-life/royals/kate-middleton-suffers-major-setback-after-cancer-diagnosis/news-story/2d4b98cb944fd251d0a94f05a9aad7b9
Kate Middleton suffers professional setback: opinion
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Rui En on her recent Instagram rebrand and dealing with criticism about her appearance
cnalifestyle.channelnewsasia.com/entertainment/rui-en-instagram-rebrand-dealing-criticism-about-appearance-387886
Rui En on her recent Instagram rebrand and dealing with criticism about ...
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This is the first thing 'Hardest Geezer' wants after a 16,000km epic run across full length of Africa
metro.co.uk/2024/04/07/hardest-geezer-completes-16-000km-run-across-africa-20601696/
This is the first thing 'Hardest Geezer' wants after a 16 ...
Profile picture of USA Today
What causes nosebleeds? And why some people get them more than others.: Nosebleeds can be the result of someone blowing their nose too hard or because an ...
usatoday.com/story/life/health-wellness/2024/04/09/what-causes-nosebleeds/73053814007/
What causes nosebleeds? And why some people get them more than others.
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Many 911 call centers are understaffed, and the job has gotten harder: More cities are adopting alternative response models, where mental health clinicians ...
npr.org/2024/04/05/1242310330/911-call-takers-police-alternative
Many 911 call centers are understaffed, and the job has gotten harder
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Suicides among a surprising population have doubled over the past 20 years, study finds
cnn.com/2024/04/10/health/student-athlete-suicide-rates-doubled-study-wellness/
Suicides among a surprising population have doubled over the past 20 years ...
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Michael Gardiner died by suicide near A47 Lynn roundabout: Retired painter and decorator, Michael Gardiner, 77, took his own life after jumping from a ...
edp24.co.uk/news/24229405.michael-gardiner-died-suicide-near-a47-lynn-roundabout/
Michael Gardiner died by suicide near A47 Lynn roundabout
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All revved up for mental health advocacy: Nothing makes an audience scream more than seeing their favourite celebrities — except seeing them do something ...
odt.co.nz/news/dunedin/all-revved-mental-health-advocacy
All revved up for mental health advocacy
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Cannabis users 'will have a new place within our society': Germany prepares to legalise home cultivation
news.sky.com/story/cannabis-users-will-have-a-new-place-within-our-society-germany-prepares-to-legalise-home-cultivation-13104010
Cannabis users 'will have a new place within our society': ...
Quick Glance: Germany Legalizes Home Cultivation: Embracing Cannabis Users in Society
  • In a large grey facility outside Dresden, Demecan grows medical cannabis. A new law decriminalizes possession and home cultivation of cannabis. Critics raise health concerns, while proponents praise the quality and tax revenues.

  • Under the new law, adults can possess up to 25g in public, hold 50g at home, and grow up to three plants. Private 'cannabis clubs' can supply 500 members on a limited basis starting in July.

  • Controlling THC potency is limited, especially for those under 21. To avoid 'drug tourism,' recreational users can only grow cannabis at home or obtain it through 'cannabis clubs.'

  • Passing the law was contentious. The government aims to curb the black market and ensure product quality, but opponents fear health risks, especially for youth. The public is divided on legalization, with a slim majority against the law.
Profile picture of The Hill (newspaper)
Why are Americans so unhappy? : Unhappiness is both a political state and a mental health crisis, although we rarely see them as interrelated. 
thehill.com/opinion/4568301-why-are-americans-so-unhappy/
Why are Americans so unhappy? 
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'Gas station heroin' nearly killed her. Why many won't talk about this 'dark secret.'
usatoday.com/story/life/health-wellness/2024/04/01/gas-station-heroin-addiction-shame-stigma/73144835007/
'Gas station heroin' nearly killed her. Why many won't talk about this ...
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Tragedy of popular accountant and footballer found dead in woodland: His mental health took a 'sudden' downturn an inquest has heard
manchestereveningnews.co.uk/news/greater-manchester-news/he-great-lad-tragedy-popular-28958165
Tragedy of popular accountant and footballer found dead in woodland
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North Wales A&E the 'worst place' claims man who 'waited 20 hours' there: Robert Mogsa, 39, from Liverpool, was visiting his aunt when he needed to seek medical ...
dailypost.co.uk/news/north-wales-news/north-wales-ae-absolutely-worst-28927233
North Wales A&E the 'worst place' claims man who 'waited 20 hours' there