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Lecanemab: First drug to slow Alzheimer’s too costly for NHS: Health assessment body NICE says the benefits “are too small to justify the costs”.
bbc.com/news/articles/c75nry66y52o
Quick Glance: Lecanemab: Costly Breakthrough in Alzheimer Treatment
- Lecanemab, the first drug shown to slow early-stage Alzheimer's, will not be available through the NHS in England as NICE deems its benefits insufficient to justify the costs, despite receiving approval from the MHRA for private prescriptions.
- In clinical trials, Lecanemab demonstrated a 25% reduction in cognitive decline over 18 months for early-stage Alzheimer's patients. However, NICE highlighted the high costs associated with treatment, including intensive monitoring and frequent hospital visits.
- Administered bi-weekly as an intravenous infusion, Lecanemab targets amyloid protein accumulation in the brain. Concerns arose regarding side effects, including small brain bleeds, leading to some patients requiring hospitalization.
- Though the benefits of Lecanemab may seem modest, it represents a significant advancement in Alzheimer's research. Health organizations expressed concern for nearly one million dementia patients facing uncertainty, while the EMA rejected its license due to serious risk concerns.
One million brain scans used to assess dementia risk: It is the first time scientists in the UK have had access to such huge volumes of valuable data.
bbc.com/news/articles/c5ylejyrvd5o
The Link Between Vision Impairment and Dementia in Older Adults: A new study found vision impairment may be to blame for nearly one in five cases of dementia.
medscape.com/viewarticle/link-between-vision-impairment-and-dementia-older-adults-2024a1000g9f
One in eight people 65 and older have Alzheimer’s disease -- and in its first stages, this devastating form of dementia may not be obvious to friends and ... Show more
When a Loved One Has Alzheimer's Disease: WebMD's caregiver's guide to understanding Alzheimer's disease symptoms and stages. Includes tips to avoid caregiver ...
webmd.com/alzheimers/ss/slideshow-alzheimers-overview
One in eight people 65 and older have Alzheimer’s disease -- and in its first stages, this devastating form of dementia may not be obvious to friends and ... Show more
When a Loved One Has Alzheimer's Disease: WebMD's caregiver's guide to understanding Alzheimer's disease symptoms and stages. Includes tips to avoid caregiver ...
webmd.com/alzheimers/ss/slideshow-alzheimers-overview
Untreated Hypertension Tied to Alzheimer's Disease Risk: Managing hypertension in older adults may reduce the risk for Alzheimer's disease ...
medscape.com/viewarticle/untreated-hypertension-tied-alzheimers-disease-risk-2024a1000fed
New study links dementia diagnosis rates to where you live in the US: Recent research has found stark gaps in dementia diagnostic practices between different ...
medicalnewstoday.com/articles/new-study-finds-stark-differences-in-dementia-diagnosis-rates-across-us
New Models Predict Time From Mild Cognitive Impairment to Dementia: Researchers made headway in developing predictive models for dementia that provide ...
medscape.com/viewarticle/new-models-predict-time-mild-cognitive-impairment-dementia-2024a1000dp1
Promising New Data Support GLP-1s for Dementia Prevention: New clinical trial data suggest promising therapeutic effects of the GLP-1 liraglutide on cognition ...
medscape.com/viewarticle/promising-new-data-support-glp-1s-dementia-prevention-2024a1000e0l
Alzheimer’s disease is the most common form of dementia. The genes you get from your parents play a part, but so do things like diet, exercise ... Show more
Things That Raise Your Chances of Dementia: Do you know the things that make you more likely to develop dementia and what you can do about them? WebMD can tell ...
webmd.com/alzheimers/ss/slideshow-raise-chances-dementia
Can music help someone with Alzheimer’s disease?: Research suggests that listening to or singing songs can provide emotional and behavioral benefits for people ...
newsnetwork.mayoclinic.org/discussion/consumer-health-can-music-help-someone-with-alzheimers-disease/
Gena Rowlands, star of ‘The Notebook,’ is living with Alzheimer’s: Gena Rowlands has Alzheimer’s, her son, director Nick Cassavetes has revealed.
cnn.com/2024/06/25/entertainment/gena-rowlands-alzheimers-wellness/
The MIND Diet That May Help Fight Alzheimer's: Alzheimer's is the most common cause of dementia in older people. Click through the WebMD slideshow to find out ...
webmd.com/alzheimers/ss/slideshow-dementia-foods
Alzheimer’s blood test catches 90% of early dementia cases, study finds: Blood tests that can detect 90% of Alzheimer’s cases could revolutionize access to ...
cnn.com/2024/07/28/health/alzheimer-blood-test-p-tau-217-wellness/
Alzheimer's drug that can slow disease gets backing from FDA advisers: Federal health advisers have endorsed a closely watched Alzheimer’s drug from Eli Lilly ...
apnews.com/article/alzheimers-drug-fda-lilly-brain-donanemab-leqembi-2e86433bf976fc627a7a81e3c58da2ba
Quick Glance: Expert Panel Backs FDA Approval of New Alzheimer’s Drug
- An independent FDA advisory committee unanimously endorsed the benefits of the new experimental Alzheimer's drug, Donanemab.
- Donanemab, manufactured by Eli Lilly, slowed cognitive decline in early-stage patients but posed significant safety risks.
- The FDA typically follows advisory committee advice, yet not always.
- Discussions on halting treatment post-amyloid clearance and the need for pre-medication tau brain scans were key highlights of the committee meeting.
The Notebook actress Gena Rowlands dies at 94: The Hollywood legend has been racking up acting awards since the 1950s.
bbc.com/news/articles/clyn3p853k5o
Quick Glance: Gena Rowlands: Tribute to a Cinematic Icon
- Gena Rowlands, the renowned actress celebrated for her intense and elegant performances, particularly in collaboration with her husband John Cassavetes, has passed away at the age of 94. Her death was confirmed by a representative of her son, Nick Cassavetes, although no details regarding the circumstances or cause were disclosed. She had been living with Alzheimer’s disease for five years.
- Rowlands received Oscar nominations for her compelling roles in 'A Woman Under the Influence' (1974) and 'Gloria' (1980), both directed by Cassavetes. Critics praised her ability to portray vulnerable and complex characters. Their collaboration in 'Faces' (1968) first brought them to the attention of independent film audiences.
- In addition to her film achievements, Rowlands won two Primetime Emmy Awards, including for her performances in 'The Betty Ford Story' (1987) and 'Face of a Stranger' (1991). She earned a total of seven Emmy nominations and was noted for her role in 'An Early Frost' (1985), one of the first films addressing the AIDS epidemic.
- Rowlands had a remarkable career spanning from the 1950s to her final appearances in 'Six Dance Lessons in Six Weeks' (2014). She received an honorary Oscar in 2015 and is survived by her husband Robert Forrest and her son. Her life and artistry profoundly influenced her perspective on the role of artists in society.
Dementia diagnosis 'not the end' for Hartlepool author: Michael Booth got his diagnosis just months after losing his mother to Alzheimer’s.
bbc.com/news/articles/c0krk0zqvg1o
FDA approves a second Alzheimer's drug that can modestly slow disease: U.S. health officials have approved a new Alzheimer’s drug that can modestly slow the ...
apnews.com/article/alzheimers-drug-kisunla-leqembi-donanemab-fd804c1271ae185a62f080e072d21698
Quick Glance: FDA Approves New Drug to Slow Alzheimer's Disease
- The FDA has approved another drug to combat Alzheimer's, allowing for a moderate slowing of the disease and providing a new option for patients in the early stages of this incurable memory disorder.
- Kisunla, the drug developed by Eli Lilly, was approved after treated patients in an 18-month study declined about 22% slower in terms of memory and cognitive abilities than those who received a placebo infusion.
- An often encountered issue with drugs targeting plaque is brain swelling and bleeding, which also applies to Kisunla.
- Compared to Leqembi, which is administered twice a month, Kisunla is given once a month, potentially making it easier for caregivers who bring their loved ones to a hospital or clinic for treatment.
How the risk of dementia can be reduced: Dementia is one of the greatest horrors of aging. But many risks can be reduced with prevention.
spektrum.de/news/demenz-erkrankungen-durch-praevention-verhindern/2226611
APOE4 Testing: To Know or Not to Know Alzheimer's Risk: Alzheimer’s disease researchers recently suggested that genetics alone could identify in advance up to ...
webmd.com/alzheimers/news/20240607/to-know-or-not-to-know-alzheimers-risk
Racing to Retake a Beloved Trip, Before Dementia Takes Everything: My dad always remembered his childhood journey through Europe. Now, with Alzheimer’s claiming ...
nytimes.com/2024/06/30/magazine/dementia-alzheimers-reminiscence-therapy.html
The Shingles Vaccine May Help Delay Dementia: The findings suggest protective powers against one of the world’s most threatening conditions.
time.com/7003667/shingles-vaccine-delay-dementia/
Two new dementia risks identified by major report: Treating failing eyesight and high cholesterol can help lower the risk of the illness, a study suggests.
bbc.com/news/articles/c84jdxd4x1ro
Quick Glance: New Insights on Dementia Prevention
- Early detection of issues through regular eye examinations
- Reducing dementia risk by treating vision problems and high cholesterol
- Identification of 14 health issues for dementia prevention
- Significant impact of healthy lifestyles and environmental factors on dementia
What is Lewy body dementia? - Harvard Health: Although less known and less understood than other types of dementia, Lewy body dementia is the second most ...
health.harvard.edu/blog/what-is-lewy-body-dementia-202407123057
Nutrition: Too much sugar is bad for the brain: Too much sugar is known to lead to obesity or diabetes. What is less well known, however ...
tagesschau.de/wissen/gesundheit/zucker-gehirn-100.html
Shingles vaccines may reduce dementia risk, two large new studies suggest: Two new studies suggest that getting a vaccine to protect against a painful case of ...
cnn.com/2024/07/30/health/shingles-vaccines-dementia-studies/
Ozempic-like weight loss drugs may protect against Alzheimer's: A weight loss drug similar to Ozempic appeared to slow cognitive decline in patients with mild ...
nbcnews.com/health/health-news/ozempic-weight-loss-drugs-may-protect-alzheimers-rcna163459
Common mental health disorder may triple risk for developing dementia, study finds
cnn.com/2024/07/29/health/anxiety-increases-dementia-risk-wellness/
8 innovations in neuroscience and brain research at Mayo Clinic: The brain is a critical, complex organ. Learn about the latest innovations in neuroscience and ...
newsnetwork.mayoclinic.org/discussion/8-innovations-in-neuroscience-and-brain-research-at-mayo-clinic/
Hull FC rugby shirt raises funds for Alzheimer’s Society: The special shirt will be worn in a Super League fixture against St Helens on 3 August.
bbc.com/news/articles/c3g91reg93no
Early signs of dementia may show up in your credit score and mortgage payments: Signs of cognitive decline can show up in everyday financial transactions ...
marketwatch.com/story/credit-scores-and-mortgage-payments-can-help-catch-dementia-early-heres-how-0f2c461c
More people are dying from dementia, according to new study: There are also ways to decrease your risk, experts say.
abcnews.go.com/Health/people-dying-dementia-new-study/story
Managing Agitation in Alzheimer's Disease: 5 Things to Know: Drs Lisa Wise and Vimal Aga discuss key aspects of agitation management in Alzheimer's disease.
medscape.com/viewarticle/managing-agitation-alzheimers-disease-5-things-know-2024a1000caf
Is It Aging or Alzheimer's?: Learn the difference between memory problems that can happen to all of us as we get older and real warning signs of dementia.
webmd.com/alzheimers/ss/slideshow-is-it-aging-or-alzheimers
Alzheimer’s risk rose up to 42% with untreated high blood pressure, study finds: Untreated high blood pressure raised the risk of Alzheimer’s by up to 42% ...
cnn.com/2024/08/14/health/blood-pressure-alzheimers-risk-wellness/
Beyond Increased Risk: APOE4 a Direct Cause of Alzheimer's?: Two copies of APOE4 may be more than just a risk factor for AD; the pair may cause the disease in ...
medscape.com/viewarticle/beyond-increased-risk-apoe4-direct-cause-alzheimers-2024a10008qx
Mayo Clinic Alzheimer’s Disease Research Center (ADRC) » Alzheimer's Disease Research Center
dementiaoutreach.mayo.edu/about/mayo-clinic-adrc/
Eating Processed Red Meat Linked to Increased Dementia Risk, Study Finds: Recent research, including a new study on processed meat, has suggested these foods can ...
nytimes.com/2024/07/31/well/eat/ultraprocessed-foods-brain-health.html
How poor sleep affects your risk of dementia and how to gauge it based on your sleep habits
cnalifestyle.channelnewsasia.com/wellness/sleep-dementia-393416
A Blood Test Accurately Diagnosed Alzheimer’s 90% of the Time, Study Finds: It was much more accurate than primary care doctors using cognitive tests and CT ...
nytimes.com/2024/07/28/health/alzheimers-blood-test.html
A new Alzheimer's study suggests where you live can affect the odds of a diagnosis
npr.org/2024/08/19/nx-s1-5080602/alzheimers-study-regional-differences-diagnosis-dementia
Is It Aging or Alzheimer's?: Learn the difference between memory problems that can happen to all of us as we get older and real warning signs of dementia.
webmd.com/alzheimers/ss/slideshow-is-it-aging-or-alzheimers
New Scripps Research study examines link between sleep and dementia in women: Alzheimer’s disease — the most common form of dementia — affects twice as many ...
nbcsandiego.com/news/local/scripps-research-sleep-brain-health-women-study/3576184/
Trump’s Speeches May Show Signs of ‘Dementia’ and Cognitive Decline, Top Experts Say
thedailybeast.com/trumps-speeches-may-show-signs-of-dementia-and-cognitive-decline-top-experts-say
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The Mayo Clinic Alzheimer’s Disease Research Center is recruiting current and former dementia caregivers to test technology that matches caregivers to one ...
mayocl.in/3WKVnOp
‘A study to give us hope’: Lifestyle changes improve Alzheimer’s symptoms for some
cnn.com/2024/06/07/health/alzheimers-dementia-ornish-lifestyle-wellness/
Rare gene mutation helps people resist Alzheimer’s disease: Researchers have discovered 27 people with a rare gene mutation called Christchurch that helped delay ...
washingtonpost.com/science/2024/06/19/alzheimers-disease-gene-treatment/
‘It comes for your very soul’: how Alzheimer’s undid my dazzling, creative wife in her 40s
theguardian.com/news/article/2024/jul/09/how-alzheimers-undid-my-dazzling-creative-wife-in-her-40s
Alzheimer's: Thousands to trial blood tests for dementia: The long-term hope is that more people will be able to access new treatments at an earlier stage.
bbc.com/news/health-68726703
Quick Glance: Nationwide Blood Test Trials Aim to Enhance Alzheimer's Diagnosis
- A variety of individuals in the UK will have the opportunity to participate in studies that could potentially revolutionize the diagnosis of Alzheimer’s.
- The blood tests could be ready for use in the NHS within five years as part of a drive to fix the nation’s low diagnosis rate.
- The University College London and the University of Cambridge will lead the trials to investigate affordable tests for proteins in individuals at early stages of dementia and those experiencing mild or progressive memory issues.
- The tests could offer results to patients significantly earlier and speed up the introduction of new Alzheimer’s medications dependent on early diagnosis.
This is how you can reduce your risk of getting dementia: People at higher genetic risk of dementia can reduce their chances of developing the neurological ...
weforum.org/agenda/2024/08/dementia-healthy-lifestyle-genetic/
I have a family history of Alzheimer’s disease. I wanted to understand my own risk
cnn.com/alzheimers-risk-test-sanjay-gupta/
Signs of Alzheimer’s were everywhere. Then his brain improved: A 55-year old man reduced signs of Alzheimer’s in his blood through lifestyle changes and a ...
cnn.com/2024/05/18/health/alzheimers-blood-brain-improvement-wellness/
Medicare explores a new way to support caregivers of dementia patients: The government is launching an experimental program to ease the burden on caregivers of ...
npr.org/sections/shots-health-news/2024/07/04/nx-s1-5026964/caregivers-dementia-alzheimers-medicare-support
Medicare explores a new way to support caregivers of dementia patients: The government is launching an experimental program to ease the burden on caregivers of ...
npr.org/sections/shots-health-news/2024/07/04/nx-s1-5026964/caregivers-dementia-alzheimers-medicare-support
Alzheimer’s: Family fears bankruptcy over care costs: Brian Witherstone, 86, from Bath, has had to wait three months for an assessment by social services.
bbc.com/news/articles/cv222rjz3ndo
Alzheimer's: I know I'm going to have early onset dementia: James Bexon knows he has less than 30 years before developing a rare form of genetic Alzheimer's.
bbc.com/news/uk-wales-68857880
For aging Japan, a troubling link between heat and dementia: The latest research indicates that heat can exacerbate cognitive decline and worsen dementia ...
japantimes.co.jp/news/2024/07/29/japan/science-health/extreme-heat-dementia-japan/
Dementia - saying goodbye to the self: The "Dementia" dossier explains what happens in the brain during cognitive decline, what contributes to dementia ...
spektrum.de/inhaltsverzeichnis/demenz-abschied-vom-ich-gug-dossier-2-2024/2203531
Genes known to increase the risk of Alzheimer’s may actually be an inherited form of the disorder, researchers say
cnn.com/2024/05/06/health/alzheimers-apoe4-gene-risk/
Quick Glance: Discovery: Alzheimer's Might Be Hereditary
- A new study suggests that Alzheimer's disease may be inherited more frequently than previously thought.
- Researchers identified a link between the APOE4 gene and a specific inherited form of Alzheimer's disease.
- Individuals with two copies of the APOE4 gene have an almost guaranteed risk of developing the biological changes associated with Alzheimer's.
- Classifying APOE4 as an inherited form of the disease has significant implications and may require personalized treatment approaches.
Mosquitoes love me!: Mosquitoes seem to have preferences and specifically choose their human victims. But after what?
spektrum.de/pdf/25-2024-spektrum-die-woche-25-2024/2203123
Make this simple dietary swap to reduce dementia risk ‘by 20 per cent’: This processed foodstuff not only damages your cardiovascular health - but your brain ...
mylondon.news/news/health/make-simple-dietary-swap-reduce-29877712
Quick Glance: E-Bikes and E-Scooters: Risky Convenience?
- The use of e-bikes and e-scooters is rapidly increasing, leading to a rise in injuries.
- From 2017 to 2022, e-bike injuries surged from 751 to 23,493, while e-scooter injuries grew by over 45% annually.
- Most accidents occurred in urban areas, with many riders not wearing helmets and some under the influence of alcohol.
- To avoid injuries, riders should wear helmets, follow traffic rules, and drive defensively.
Moving update on Coronation Street icon Julie Goodyear's dementia battle: Coronation Street fans have been updated about Bet Lynch star Julie Goodyear's ...
metro.co.uk/2024/06/11/moving-update-coronation-street-icon-julie-goodyears-dementia-battle-21009940/
This could increase your risk of Alzheimer's disease more than anything: study: Researchers say that exposure to bright outside lights at night could increase ...
nypost.com/2024/09/06/lifestyle/light-pollution-may-raise-risk-of-alzheimers-disease-study/
Quick Glance: Link Between Light Pollution and Alzheimer's Risk
- A national study indicates that exposure to artificial outdoor light at night increases the risk of Alzheimer's disease.
- Analysis of light pollution data and Medicare claims revealed a higher prevalence of Alzheimer's in areas with greater nighttime light intensity.
- Notably, for individuals under 65, the association between light intensity and Alzheimer's prevalence surpassed that of other risk factors.
- The researchers call for further studies to explore the mechanisms behind this vulnerability, suggesting light pollution may disrupt sleep and promote inflammatory processes.
US rock singer Jack Russell dies: Frontman of the band Great White is dead: The frontman of the rock band Great White died as a result of so-called Lewy body ...
berliner-zeitung.de/news/us-rocksaenger-jack-russell-gestorben-frontmann-von-band-great-white-ist-tot-li.2245498
Quick Glance: Jack Russell: Rock Icon Passes Away at 63
- Jack Russell, the lead singer of the iconic 1980s hard rock band Great White, has died at the age of 63. His death was attributed to Lewy body dementia and multiple system atrophy, as reported by K.L. Doty, the author of his autobiography.
- Russell co-founded Great White in 1982, initially performing in small clubs in Southern California. The band changed its name in 1984, and their hit 'Rock Me' reached No. 60 on the Billboard Hot 100 in 1987. Their biggest success came with 'Once Bitten Twice Shy,' which peaked at No. 5 in 1989 and earned a Grammy nomination in 1990.
- In 2003, a pyrotechnics display at the Station Nightclub in Rhode Island led to a catastrophic fire that killed 100 people, including the band's guitarist. Although Russell faced no charges, the band agreed to a $1 million settlement related to the tragedy.
- After facing various personal and professional challenges, Russell announced his retirement in 2023 due to health issues, despite continuing his musical career with Jack Russell's Great White. He is survived by his wife Heather Ann and his son Matthew Hucko.
Time to act on Dementia: World Alzheimer’s Month highlights urgent need to raise awareness and tackle stigma - Dominica News Online
dominicanewsonline.com/news/homepage/news/time-to-act-on-dementia-world-alzheimers-month-highlights-urgent-need-to-raise-awareness-and-tackle-stigma/
Beloved mum received worrying health news after assuming she was just stressed: Josephine Morton initially thought her memory issues were down to the stresses of ...
gloucestershirelive.co.uk/news/health/beloved-mum-received-worrying-health-9521167
Bruce Willis' daughter shares update on his dementia battle: Bruce Willis' daughter Tallulah has opened up about her father's battle with ...
walesonline.co.uk/lifestyle/showbiz/bruce-willis-daughter-shares-update-29838772
Scots Health Sec bought Oasis tickets during dementia panel: After a hopeful speech from an industry expert, Mr Gray said: “I’m in the queue to to buy Oasis ...
heraldscotland.com/news/24555039.scots-health-sec-bought-oasis-tickets-dementia-panel/
New Alzheimer’s drug in demand but who should take it?: USF’s Memory Disorders Clinic fielding requests from patients and their families hoping that Donanemab ...
tampabay.com/news/health/2024/08/22/alzheimers-fda-donanemab-dementia-medication/
Doctors say take 2p pill every day now to stop getting dementia: NHS officials and experts including Michael Mosley have advocated taking a cheap supplement ...
gloucestershirelive.co.uk/news/health/doctors-say-take-2p-pill-9534689
One condition with Alzheimers-like symptoms has 100% PIP success rate: Out of the 547 conditions recorded in the DWP's report for 2023, only one had a full ...
bristolpost.co.uk/news/health/one-condition-alzheimers-like-symptoms-9492619
Acute kidney injury linked to higher risk of some forms of dementia: Researchers have found that experiencing acute kidney injury may increase a person's chances ...
medicalnewstoday.com/articles/acute-kidney-injury-linked-to-higher-risk-of-some-forms-of-dementia
Two diets are best for reducing dementia risk, professor says: Professor June Andrews says there is one rule for determining if a food is good for your brain ...
cambridge-news.co.uk/news/health/two-diets-best-reducing-dementia-29850988
Diabetes drugs may offer hope as dementia treatment: Researchers also found a 39 per cent reduced risk for Alzheimer’s disease
thenationalnews.com/health/2024/08/28/diabetes-drugs-may-offer-hope-as-dementia-treatment/
Your ZIP code may determine your dementia diagnosis, study finds: Depending on your ZIP code, you may be twice as likely to be diagnosed with dementia in some ...
richmond.com/life-entertainment/nation-world/wellness/dementia-alzheimers-disease-diagnosis-location-study/article_b04952c1-0965-5267-86c0-abdf4fe11a5e.html
Dementia - | and then? Experts from Winnenden on the signs and treatment: Dementia - | and then? Experts from Winnenden on the signs and treatment - | News from ...
zvw.de/lokales/winnenden/dement-und-dann-experten-aus-winnenden-%C3%BCber-anzeichen-und-behandlung_arid-864286
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Long COVID patients have similar brain activity to those with dementia, UK researchers find
kentucky.com/news/health-and-medicine/article292187465.html
Could potassium levels in blood help diagnose Alzheimer’s early?: Using geochemistry, scientists have identified a new blood biomarker that could help diagnose ...
medicalnewstoday.com/articles/could-potassium-levels-in-blood-help-diagnose-alzheimers-early
Platinum-selling 1980s rocker dies, aged 63, after dementia diagnosis: It comes a month after he announced his retirement saying he was no longer able to perform ...
walesonline.co.uk/lifestyle/showbiz/platinum-selling-1980s-rocker-dies-29750265
Relocation of Peterborough's Dementia Resource Centre will have 'as minimal impact as possible' on service users, says council
peterboroughtoday.co.uk/health/relocation-of-peterboroughs-dementia-resource-centre-will-have-as-minimal-impact-as-possible-on-service-users-says-council-4774476
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